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本院自1977年1月至1982年1月共收治新生儿(出生至28天)惊厥病人98例,占住院新生儿病人的9.2%,惊厥发生率较高。其中低体重儿惊厥发生率占住院低体重儿的27.2%,比住院足月新生儿惊厥发生率(7%)明显增高(P<0.001)。病因比较复杂,颅脑损伤(37.6%)和低血钙(27.7%)是新生儿惊厥的主要病因,其次为感染(7%)、低血糖(2%)等,原因不明者占(12.8%)。惊厥发作形式主要为限局性阵挛性发作,其次为全身性阵挛性发作和轻微发作。本组新生儿惊厥病死率为17.3%,低体重儿约占死亡病例的一半(47.1%)。均死于原发病。随访39例(8月~5 1/2岁),后遗症发生率为28.2%(11/39)。颅脑损伤是本组病人死亡和后遗症的重要原因。
The hospital from January 1977 to January 1982 were treated neonate (birth to 28 days) 98 cases of convulsions, accounting for 9.2% of hospitalized neonates, convulsions were higher. The incidence of seizures in low birth weight children accounted for 27.2% of hospitalized children with low birth weight, which was significantly higher than that of full term neonatal sedentary children (7%) (P <0.001). The etiology is complex, with traumatic brain injury (37.6%) and hypocalcemia (27.7%) being the major cause of neonatal seizures, followed by infection (7%) and hypoglycemia (2% ). Seizures mainly in the form of partial clonic seizures, followed by systemic clonic seizures and minor attacks. Fetal convulsion convulsions in this group was 17.3%, low birth weight accounted for about half of the deaths (47.1%). All died of primary disease. Follow-up 39 cases (August ~ 5 1/2 years), the incidence of sequelae was 28.2% (11/39). Brain injury is an important cause of death and sequelae in this group of patients.