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为探讨温胆汤治疗精神神经疾患的作用机理，观察了该方对小鼠自主活动、攀爬行为及抬头活动等整体行为的影响。结果：与生理盐水对照组比较，温胆汤全方与氯丙嗪均能明显减少正常小鼠自发活动（Ｐ＜０．０１），减少去水吗啡诱发的小鼠攀爬行为（Ｐ＜０．０１），减少Ｌ－多巴诱发的小鼠抬头活动（Ｐ＜０．０１），但温胆汤抑制效果弱于氯丙嗪（Ｐ＜０．０１）。提示温胆汤有良好的安定作用，从而可治疗精神神经疾患
In order to investigate the mechanism of Wendan Decoction treatment of mental neurological disorders, the effects of this prescription on the overall behavior of mice such as autonomic activity, climbing and head-up activities were observed. RESULTS: Compared with the saline control group, both Wendan Decoction and chlorpromazine significantly reduced the spontaneous activity of normal mice (P<0.01), and decreased the mice morphine-induced mice’s climbing (P<0.01). ), L-dopa-induced mouse head-up activity was reduced (P<0.01), but Wendan decoction was weaker than chlorpromazine (P<0.01). Tip warm soup has a good stability, which can treat mental disorders