论文部分内容阅读
目的 探讨易发生子宫内膜增生的多囊卵巢综合征 (PCOS)的临床表型特点 ,以指导临床监测与防治。方法 采用前瞻性的研究方法对 76例PCOS者行子宫内膜增生病理、闭经时间、体质指数 (BMI)及胰岛素抵抗和雄激素水平间关系的研究。结果 76例PCOS者中 1 9例子宫内膜单纯增生 ,3例非典型增生 ;雄激素水平的高低与子宫内膜增生无关 ;胰岛素抵抗、肥胖和闭经≥ 3个月与子宫内膜增生密切相关。结论 PCOS胰岛素抵抗、肥胖、月经类型及年龄与子宫内膜增生有密切关系 ,多囊卵巢综合征患者详细的月经资料及体质指数对确定子宫内膜病变的高危人群有极大的邦助。
Objective To investigate the clinical phenotypic characteristics of polycystic ovary syndrome (PCOS) prone to endometrial hyperplasia to guide clinical monitoring and prevention. Methods A prospective study of 76 patients with PCOS underwent endometrial hyperplasia pathology, amenorrhea time, body mass index (BMI) and insulin resistance and the relationship between the level of androgen. Results Among the 76 PCOS patients, there were only 19 cases of endometrial hyperplasia and 3 cases of atypical hyperplasia. The level of androgen was not associated with endometrial hyperplasia. Insulin resistance, obesity and amenorrhea ≥ 3 months were closely related to endometrial hyperplasia . Conclusion PCOS insulin resistance, obesity, type and age of menstruation and endometrial hyperplasia are closely related. The detailed menstrual data and body mass index of patients with PCOS have a great help to identify high-risk endometrial lesions.