作者对低体重新生儿的病变进行研究。发现耳聋是一个大问题,占15.9%。原因是发育不全、耳毒性药物、暖箱噪声及低氧血症和酸中毒一类的围产期并发症,后者常可造成脑部病变。这些病变引起耳聋的机制不明。本文对低体重新生儿耳聋发病机制及发病率情况进行研究。 1971～1973年间作者共遇到1800克以下新生儿235名,存活者136名。1978～1979年间进行随访的有98名,随访平均年龄为6(1/2)岁。随访包括体检、眼科、神经科、耳科检查。新生儿处理包括疾病的预防及供给充足的营养,前者包括低氧 The authors studied the pathogenesis of low birth weight infants. Deafness is a big problem, accounting for 15.9%. The cause is hypoplasia, ototoxic drugs, warm box noise and perinatal complications such as hypoxemia and acidosis, which often cause brain lesions. The mechanisms by which these lesions cause deafness are unknown. This article studies the pathogenesis and incidence of deafness in low birth weight infants. Between 1971 and 1973, the authors encountered a total of 235 newborns below 1800 grams and 136 survivors. There were 98 follow-up visits between 1978 and 1979 with a mean follow-up of 6 (1/2) years. Follow-up included physical examination, ophthalmology, neurology, and otology. Neonatal treatment includes prevention of disease and adequate nutrition, the former including hypoxia