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目的研究一种复方季铵盐消毒剂对嗜肺军团菌杀灭效果及其影响因素。方法应用悬液定量杀菌试验方法,对以二癸基二甲基氯化铵为杀菌成分的复方季铵盐消毒液杀灭嗜肺军团菌的效果及其影响因素进行了观察。结果以活性物含量为59.2 mg/L的该复方季铵盐消毒剂对悬液内嗜肺军团菌作用5 min,平均杀灭对数值>5.0。该复方季铵盐消毒剂随浓度增加和作用时间延长,其杀菌作用增强;但其随消毒液pH值降低,杀菌作用减弱。结论该复方季铵盐消毒剂在较低浓度下对嗜肺军团杆菌杀灭效果较好,但消毒液pH值偏酸性会降低其杀菌效果。
Objective To study the killing effect of compound quaternary ammonium disinfectant on Legionella pneumophila and its influence factors. Methods The method of suspension quantitative sterilization was applied to observe the effect of compound quaternary ammonium salt disinfectant with didecyl dimethyl ammonium chloride as a bactericidal agent to kill Legionella pneumophila and its influencing factors. Results The compound quaternary ammonium salt disinfectant with the active content of 59.2 mg / L exerted 5 min on Legionella pneumophila in suspension with an average killing logarithm> 5.0. The compound quaternary ammonium disinfectant with increasing concentration and prolonged action, the bactericidal effect increased; but with the disinfectant pH value decreased, the bactericidal effect weakened. Conclusion The compound quaternary ammonium disinfectant has a good killing effect on Legionella pneumophila at lower concentration, but its acidity will reduce its bactericidal effect.