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目的 观察动脉插管化疗联合放射治疗头颈部恶性肿瘤的疗效。方法 对 41例头颈部恶性肿瘤患者采用颞浅动脉逆行插管 (ICAT) ,灌注化疗药物 ,其中DDP 2 0mg× 5 ,5 -Fu 5 0 0mg× 5 ,BLM 8mg× 2。插管化疗 2周后开始常规放射治疗。原发灶剂量为 60 0 0～ 70 0 0cgy/ 6～ 7W。颈部转移淋巴结处为 5 0 0 0～ 60 0 0cgy/ 5～ 6W ,均采用 60CO照射。结果 动脉插管至放疗前有 2 8例患者鼻塞、头痛、耳鸣等症状缓解 ,有 18例原发灶及转移肿物缩小。放疗后 4周的疗效判定 :2 8例CR ,6例PR ,总有效率 82 9%。结论 通过对本组 41例的观察 ,认为颞浅动脉逆行插管联合放射治疗头颈部恶性肿瘤是一种疗效好、安全、毒副作用小的治疗手段目的 观察动脉插管化疗联合放射治疗头颈部恶性肿瘤的疗效。方法 对 41例头颈部恶性肿瘤患者采用颞浅动脉逆行插管 (ICAT) ,灌注化疗药物 ,其中DDP 2 0mg× 5 ,5 -Fu 5 0 0mg× 5 ,BLM 8mg× 2。插管化疗 2周后开始常规放射治疗。原发灶剂量为 60 0 0～ 70 0 0cgy/ 6～ 7W。颈部转移淋巴结处为 5 0 0 0～ 60 0 0cgy/ 5～ 6W ,均采用 60CO照射。结果 动脉插管至放疗前有 2 8例患者鼻塞、头痛、耳鸣等症状缓解 ,有 18例原发灶及转移肿物缩小。放疗后 4周的疗效判定 :2 8例CR ,6?
Objective To observe the curative effect of arterial intubation chemotherapy combined with radiotherapy on head and neck malignant tumor. Methods Forty-one patients with malignant head and neck cancer underwent retrograde superficial temporal artery catheterization (ICAT) with chemotherapeutic drugs, including DDP 2 0mg × 5, 5-Fu × 500mg × 5 and BLM 8mg × 2. After 2 weeks of intubation and chemotherapy, conventional radiotherapy was started. The primary dose of 60 0 0 ~ 70 0 0 cgy / 6 ~ 7W. Neck metastasis lymph nodes at 500 ~ 60 0cgy / 5 ~ 6W, were used 60CO irradiation. Results Before arterial catheterization, 28 patients had nasal congestion, headache, tinnitus and other symptoms were relieved. There were 18 cases of primary lesion and metastatic tumor shrinking. 4 weeks after radiotherapy to determine the efficacy: 28 cases of CR, 6 cases of PR, the total effective rate of 82 9%. Conclusion Through the observation of 41 cases in this group, retrospective superficial temporal artery intubation combined with radiotherapy of head and neck cancer is a good treatment, safe, small side effects of the treatment of the purpose of arterial intubation chemotherapy combined with radiotherapy head and neck Efficacy of malignant tumors. Methods Forty-one patients with malignant head and neck cancer underwent retrograde superficial temporal artery catheterization (ICAT) with chemotherapeutic drugs, including DDP 2 0mg × 5, 5-Fu × 500mg × 5 and BLM 8mg × 2. After 2 weeks of intubation and chemotherapy, conventional radiotherapy was started. The primary dose of 60 0 0 ~ 70 0 0 cgy / 6 ~ 7W. Neck metastasis lymph nodes at 500 ~ 60 0cgy / 5 ~ 6W, were used 60CO irradiation. Results Before arterial catheterization, 28 patients had nasal congestion, headache, tinnitus and other symptoms were relieved. There were 18 cases of primary lesion and metastatic tumor shrinking. 4 weeks after radiotherapy to determine the efficacy: 28 cases of CR, 6?