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目的了解南充市梅毒发病水平和流行特征,为制定梅毒防制策略提供科学依据。方法收集2004-2012年南充市传染病网络直报系统报告梅毒病例,结合辖区某三甲医院就诊一般患者梅毒抗体筛查资料,进行描述流行病学分析。结果 2004-2012年南充市累计报告梅毒7 396例,死亡1人,年均报告发病率为12.43/10万,年平均增长速度1261.60%,各年度发病率差异有统计学意义(P<0.01)。报告梅毒病例分期以隐形梅毒最高为2 456例(46.71%)。每月均有病例报告,季节性高峰不明显。男女性别比为0.93∶1;发病年龄以20~49岁年龄组为主,职业分布以农民为主。年均报告发病率居前3位的县(区)是顺庆区、高坪区和蓬安县。临床就诊一般患者的梅毒抗体筛查阳性率为7.86%。结论南充市2004-2012年梅毒发病率呈逐年上升趋势,应开展以社区基本公共卫生服务为依托的综合干预措施。
Objective To understand the prevalence and epidemiological characteristics of syphilis in Nanchong city and to provide a scientific basis for formulating syphilis prevention and control strategies. Methods The cases of syphilis were collected from network reporting system of communicable diseases in Nanchong City from 2004 to 2012, and the syphilis antibody screening data of common patients in some top three hospitals in the area were collected to describe the epidemiological analysis. Results A total of 7 396 syphilis cases were reported in Nanchong City from 2004 to 2012, with an average annual death rate of 12.43 / lakh and an average annual growth rate of 1261.60%. There were significant differences in the annual incidence rates (P <0.01) . The syphilis cases staged with stealth syphilis up to a maximum of 2 456 cases (46.71%). There are monthly reports of cases, the seasonal peak is not obvious. The male-female ratio was 0.93: 1. The age of onset was mainly in the age group of 20-49, and the distribution of occupations was dominated by peasants. The top 3 counties (districts) with annual average reported incidence are Shunqing District, Gaoping District and Peng’an County. The positive rate of syphilis antibody screening in general clinic patients was 7.86%. Conclusions The incidence of syphilis in Nanchong from 2004 to 2012 shows an increasing trend year by year. Comprehensive interventions based on community basic public health services should be carried out.