Ｔｅｎａｓｃｉｎ是细胞外基质中一个具有独特的六臂体结构的寡聚糖蛋白家族。它在胚胎发生过程中特定的时期和部位合成，在成人组织中存在于很局限的部位，而在多种肿瘤组织中都有突出的表达。其表达受到许多细胞因子及糖皮质激素的调节，还受机械压力的影响。它的作用目前尚不十分清楚，可能是一种粘附抑制因子，在肿瘤的发生中可能起着促进上皮细胞增生的作用 Tenascin is an oligomeric glycoprotein family with a unique six-arm structure in the extracellular matrix. It is synthesized during specific stages and parts of the embryogenesis, exists in very limited areas in adult tissues, and has prominent expression in various tumor tissues. Its expression is regulated by many cytokines and glucocorticoids and is also affected by mechanical stress. Its role is not yet clear, may be an adhesion inhibitor, in the tumor may play a role in promoting epithelial cell proliferation