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目的探究静脉复合麻醉联合吸入麻醉在乳腺癌根治术中的应用效果。方法选择2012年2月—2014年3月收治的乳腺癌根治术患者80例纳入本次研究,随机分为对照组和研究组各40例。对照组患者采用吸入麻醉方式,研究组采用静脉复合麻醉联合吸入麻醉方式。记录并比较两组麻醉诱导时间、麻醉时间、手术时间、停药至拔管时间及麻醉前、麻醉过程中、术后患者SBP、DBP、HR及Sp O2水平变化情况,观察两组并发症发生情况。计量资料组间比较采用t检验,组内比较采用配对t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果研究组麻醉时间、停药至拔管时间分别为(76.42±8.32)、(8.42±3.13)min,均优于对照组的(83.33±7.44)、(15.31±4.52)min,差异均有统计学意义(均P>0.05)。麻醉15 min时,研究组SBP、DBP、HR分别为(103.34±8.76)、(62.82±3.24)mm Hg(1 mm Hg=0.133 k Pa)、(72.32±8.94)次/min,均低于对照组的(114.40±7.53)、(68.73±4.32)mm Hg、(80.41±7.86)次/min,差异均有统计学意义(均P<0.05)。研究组并发症发生率为7.5%,低于对照组的32.5%,差异有统计学意义(P<0.05)。结论在乳腺癌根治术中采用静脉复合麻醉联合吸入麻醉方法效果较好,值得推广使用。
Objective To investigate the effect of intravenous combined anesthesia combined with inhalation anesthesia in radical mastectomy of breast cancer. Methods Eighty patients with breast cancer undergoing radical surgery from February 2012 to March 2014 were enrolled in this study and randomly divided into control group and study group with 40 cases each. Patients in the control group were given inhalation anesthesia. The study group used intravenous anesthesia combined with inhalation anesthesia. The changes of SBP, DBP, HR and Sp O2 levels were recorded and compared between the two groups after anesthesia induction time, anesthesia time, operation time, withdrawal time to extubation, anesthesia, anesthesia and postoperative complication Happening. Measurement data were compared between groups using t test, the group was compared using paired t test, count data using χ2 test, P <0.05 for the difference was statistically significant. Results The time from anesthesia to extubation in the study group were (76.42 ± 8.32) and (8.42 ± 3.13) min, respectively, which were better than those in the control group (83.33 ± 7.44 and 15.31 ± 4.52) min, respectively Significance (both P> 0.05). SBP, DBP and HR in the study group were (103.34 ± 8.76), (62.82 ± 3.24) mm Hg (1 mm Hg = 0.133 kPa) and (72.32 ± 8.94) times / min respectively at 15 min after anesthesia, Group (114.40 ± 7.53), (68.73 ± 4.32) mm Hg, (80.41 ± 7.86) times / min, the difference was statistically significant (all P <0.05). The complication rate of the study group was 7.5%, which was lower than that of the control group (32.5%), the difference was statistically significant (P <0.05). Conclusions Intravenous combined anesthesia combined with inhalation anesthesia in radical mastectomy is effective and worth promoting.