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目的 :探讨胃肠道腺癌细胞核DNA含量与腺癌组织学分类、分级及其预后的关系。方法 :应用国产的CMIAS 真彩色医学图象分析系统 ,对 93例胃腺癌 ,6 3例肠腺癌癌细胞核进行DNA测定。结果 :腺癌细胞核的DNA含量相对倍体均量 (μ值 )与组织学分级有统计学意义 (P <0 0 5 )。 结论 :胃肠道腺癌细胞DNA含量的变化 ,可作为反映肿瘤增殖能力的主要生物学指标。肿瘤的恶性程度与DNA含量密切相关。但粘液腺癌与粘液细胞癌有其特殊性 ,应予注意
Objective: To investigate the relationship between nuclear DNA content in adenocarcinoma cells and the histological classification, grading and prognosis of adenocarcinoma. Methods: The domestic CMIAS true color medical image analysis system was used to detect the DNA of 93 cases of gastric adenocarcinoma and 63 cases of intestinal adenocarcinoma. Results: The DNA content of adenocarcinoma nucleus showed statistically significant (P <0 05) relative ploidy (μ value) and histological grade. Conclusion: The change of DNA content in gastrointestinal adenocarcinoma cells can be used as the main biological index to reflect the tumor proliferation ability. The degree of malignancy and DNA content are closely related. However, mucinous adenocarcinoma and mucinous cell carcinoma has its particularity, should be noted