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目的:通过观察宫腔占位病变的超声造影特征,分析良、恶性占位时间-强度曲线量化指标的差异,为临床早期发现内膜恶性病变提供更准确的参考依据。方法:分别对78例宫腔占位(良性46例,恶性32例)进行外周静脉超声造影检查,分析宫腔内病灶灌注增强方式;使用Qlab脱机分析软件,获得时间-强度曲线(TIC),比较良性组与恶性组间上升时间、达峰时间、峰值强度、半降时间及内洗斜率等指标,对病灶的良恶性提供初步诊断。结果:宫腔内病灶造影灌注的方式有三种:整体快速增强、周边向中央汇聚、中央向外周灌注,第一种方式在恶性组中多见(28/32,87.5%),后两种多见于良性病灶(39/46,84.8%);TIC量化指标中上升时间、达峰时间、半降时间及内洗斜率在两组中具有显著统计学差异,峰值强度在组间无统计学差异。结论:通过超声造影成像技术及量化指标分析能初步鉴别宫腔占位性病变良恶性,为临床提供更多诊断信息。
OBJECTIVE: To observe the contrast echocardiographic features of uterine space occupying lesion and analyze the difference of quantitative indicators of time-intensity curve of benign and malignant space occupying lesions, so as to provide more accurate reference for detecting endometrial malignant lesions in early stage. Methods: Peripheral venous ultrasonography was performed in 78 cases of uterine cavity (46 cases of benign and 32 cases of malignant), and the enhancement of intrauterine lesion perfusion was analyzed. Using Qlab offline analysis software, the time-intensity curve (TIC) , The benign and malignant groups were compared between the rise time, peak time, peak intensity, half down time and the rate of internal wash slope and other indicators to provide a preliminary diagnosis of benign and malignant lesions. Results: There are three ways of intracavitary focal contrast-enhanced perfusion: rapid overall enhancement, peripheral convergence to the central, peripheral perfusion from the center, the first one is more common in the malignant group (28/32, 87.5%), the latter two more Found in benign lesions (39/46, 84.8%); TIC quantitative indicators of the rise time, peak time, half down time and internal wash slope in the two groups had significant statistical differences, peak intensity in the group was no significant difference. Conclusion: Through the contrast-enhanced ultrasound imaging and quantitative analysis of the indicators, we can initially identify the malignant lesions of uterine space-occupying lesions and provide more information for clinical diagnosis.