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作者将36名HBsAg、抗-HBs和抗-HBc阴性的健康青年分为两组:研究组由12名男性和5名女性组成,平均年龄为24.6岁;对照组由10名男性和9名女性组成,平均年龄为24.4岁。研究组分别于0、1和12个月接种3剂血源性乙型肝炎疫苗。对照组则按0、1和6个月的常规程序接种。受试者均用同批疫苗于上臂作肌肉注射。在第1针后2、6、7、13和36个月采血,用放射免疫法检测
The study divided 36 healthy children with HBsAg, anti-HBs and anti-HBc into two groups: the study group consisted of 12 males and 5 females, with an average age of 24.6 years; the control group consisted of 10 males and 9 females Composition, the average age of 24.4 years old. The study group were vaccinated 3 doses of blood-borne hepatitis B vaccine at 0, 1 and 12 months respectively. The control group was vaccinated by routine procedures of 0, 1 and 6 months. Subjects were given the same batch of vaccine in the upper arm for intramuscular injection. Blood samples were taken at 2, 6, 7, 13 and 36 months after the first stitch and detected by radioimmunoassay