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目的探讨癌胚抗原(CEA)、CA199、CA242、联合糖类抗原CA50检测对胰腺癌诊断的临床价值。方法选取2009年2月至2012年3月本院住院治疗的胰腺癌患者42例为观察组,选择门诊体检的健康人42例为对照组,分别对两组人群进行CEA、CA199、CA242、CA50检测。结果检测结果显示:观察组CEA、CA199、CA242、CA50含量水平明显高于对照组(P<0.05),差异具有统计学意义,且联合检测特异性和敏感性高于检测单一指标。结论 CEA、CA199、CA242、联合CA50检测,对胰腺癌诊断的特异性和敏感性高,具有较高临床价值。
Objective To investigate the clinical value of detection of carcinoembryonic antigen (CEA), CA199, CA242 and combined carbohydrate antigen CA50 in the diagnosis of pancreatic cancer. Methods Forty-two patients with pancreatic cancer hospitalized in our hospital from February 2009 to March 2012 were selected as the observation group and 42 healthy individuals selected as the control group were enrolled in the study. CEA, CA199, CA242 and CA50 Detection. Results The test results showed that the levels of CEA, CA199, CA242 and CA50 in the observation group were significantly higher than those in the control group (P <0.05). The differences were statistically significant, and the specificity and sensitivity of the combined detection were higher than the single index. Conclusion CEA, CA199, CA242, combined with the detection of CA50, pancreatic cancer diagnosis of high specificity and sensitivity, with high clinical value.