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目的比较阿苯达唑和甲苯咪唑治疗包虫病的经济效果。方法选择2014-2015年在新疆医科大学第一附属医院住院治疗的包虫病患者108例,随机分成阿苯达唑组和甲苯咪唑组,分别给予治疗。运用药物经济学的成本效果分析方法进行分析。结果阿苯达唑组治疗的有效率为57.9%,甲苯咪唑组治疗的有效率为51.0%;阿苯达唑组的成本-效果比(C/E)为14.6%,甲苯咪唑组的C/E为34.7%;阿苯达唑组的不良反应发生率为3.5%,甲苯咪唑组的不良反应发生率为5.9%。结论阿苯达唑组和甲苯咪唑组方案治疗包虫病,临床总有效率无明显差异,阿苯达唑治疗包虫病的经济学成本较好。
Objective To compare the economic effects of albendazole and mebendazole in the treatment of hydatid disease. Methods A total of 108 patients with hydatid disease hospitalized in the First Affiliated Hospital of Xinjiang Medical University from 2014 to 2015 were randomly divided into albendazole group and mebendazole group and were given respectively. The use of cost-effectiveness analysis of drug economics methods for analysis. Results The effective rate was 57.9% in albendazole group and 51.0% in mebendazole group. The C / E ratio in albendazole group was 14.6%. The C / E was 34.7%. The incidence of adverse reactions in albendazole group was 3.5%, and the incidence of adverse reactions in mebendazole group was 5.9%. Conclusions Albendazole group and mebendazole regimen for the treatment of hydatid disease, the total effective rate was no significant difference, albendazole treatment of hydatid disease, the economic cost is better.