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目的分析初诊2型糖尿病采用胰岛素泵短期持续皮下注射胰岛素类似物治疗的临床效果。方法选取我院84例初诊2型糖尿病患者,并随机将其分为治疗组(42例)和对照组(42例),对照组患者采用皮下注射胰岛素进行治疗,治疗组患者采用胰岛素泵短期持续皮下注射胰岛素类似物治疗,对比两组患者临床治疗效果。结果两组患者治疗前空腹血糖、糖化血红蛋白、早餐后血糖、晚餐后血糖及睡前血糖无显著差异性(P>0.05);治疗后,两组患者糖化血红蛋白较治疗前无显著变化(P>0.05);两组患者治疗后空腹血糖、早餐后血糖、晚餐后血糖及睡前血糖较治疗前存在显著差异性(P<0.05);组间对比,治疗组患者治疗后空腹血糖、糖化血红蛋白、早餐后血糖、晚餐后血糖及睡前血糖显著优于对照组患者(P<0.05);两组患者不良反应发生率有统计学意义(P<0.05)。结论胰岛素泵短期持续皮下注射胰岛素类似物在治疗初诊2型糖尿病患者中效果显著。
Objective To analyze the clinical effect of short-term continuous insulin subcutaneous injection of insulin analogues on newly diagnosed type 2 diabetes patients with insulin pump. Methods Eighty-four patients with newly diagnosed type 2 diabetes mellitus were selected and randomly divided into treatment group (42 cases) and control group (42 cases). Patients in control group were treated with subcutaneous injection of insulin. Patients in treatment group were treated with insulin pump for short term Subcutaneous insulin analogue treatment, compared the clinical efficacy of two groups of patients. Results Before treatment, there was no significant difference in fasting blood glucose, glycosylated hemoglobin, postprandial blood glucose, postprandial blood glucose and blood sugar before going to sleep (P> 0.05). After treatment, there was no significant change in HbA1c between the two groups before treatment (P> 0.05). After treatment, fasting blood glucose, postprandial blood glucose, postprandial blood glucose and blood glucose before going to sleep were significantly different between the two groups (P <0.05). After treatment, the fasting blood glucose, glycosylated hemoglobin, The postprandial blood glucose, postprandial blood glucose and bedtime blood glucose were significantly better than those in the control group (P <0.05). The incidence of adverse reactions in the two groups was statistically significant (P <0.05). Conclusion Short-term continuous insulin subcutaneous injection of insulin analogues in the treatment of newly diagnosed type 2 diabetes patients with significant effect.