先天性红细胞生成异常性贫血 (ＣＤＡ)是一种罕见的遗传性骨髓病变 ,ＣＤＡⅠ型电镜检查的特有改变为骨髓原红细胞核呈海绵状伴广泛核膜破坏。本病常表现为中度贫血 ,严重者可有胎儿水肿。新生儿持续性 ,肺动脉高压 (ＰＰＨＮ) (与肺血管抵抗抑制肺血流有关 ) ,动脉导管和卵圆 Congenital erythropoietic anemia (CDA) is a rare hereditary bone marrow disease, CDA Ⅰ-type electron microscopy of the specific changes in the nucleus of the primitive red blood cells was spongiform cambium with the destruction of the extensive nuclear membrane. The disease often showed moderate anemia, severe cases may have fetal edema. Neonatal Persistence, Pulmonary Hypertension (PPHN) (Associated with Pulmonary Vascular Restriction, Pulmonary Blood Flow), Artery Catheters and Oval