肿瘤是多基因、多因素相互作用的网络调控的结果。目前,肿瘤的发病率及死亡率均居高不下,而传统的治疗技术(如手术、放疗、化疗)又难以完全抑制或逆转肿瘤细胞的生长,因此,有待发展新的、更有效的治疗方法。文中对近年来RNA干扰(RNA i)技术在肿瘤基因靶向治疗上的进展作一综述。 Tumors are the result of multi-gene, multi-factor interaction network regulation. At present, the morbidity and mortality of tumors are both high, and the traditional treatment techniques (such as surgery, radiotherapy, chemotherapy) are difficult to completely inhibit or reverse the growth of tumor cells. Therefore, new and more effective treatments to be developed . In this paper, the progress of RNA interference (RNAi) technology in tumor gene therapy in recent years is reviewed.