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目的探讨缩宫素联合米索前列醇用于产后出血治疗的临床疗效。方法 2012年3月至2013年3月期间,本院诊治的120例自然分娩产妇,随机分为对照组(缩宫素治疗)和观察组(缩宫素联合米索前列醇治疗),每组各60例,对两组产程变化、产后30min和2h出血量,以及不良反应,进行观察和比较。结果与对照组相比,观察组第三产程时间明显缩短,产后30min和2h出血量明显减少,并发症发生率显著降低,P<0.05,差异有统计学意义。治疗期间,两组都没有出现明显的不良反应。结论缩宫素联合米索前列醇可有效预防产后出血,值得临床广泛推广。
Objective To investigate the clinical effect of oxytocin combined with misoprostol in the treatment of postpartum hemorrhage. Methods From March 2012 to March 2013, 120 cases of spontaneous labor in our hospital were randomly divided into control group (oxytocin treatment) and observation group (oxytocin combined with misoprostol treatment), and each group 60 cases in each group. The change of labor process, the amount of hemorrhage 30min and 2h postpartum and the adverse reaction were observed and compared. Results Compared with the control group, the duration of the third stage of labor in the observation group was significantly shortened, the amount of bleeding at 30 and 2 hours postpartum was significantly reduced, the incidence of complications was significantly reduced, P <0.05, the difference was statistically significant. During treatment, no apparent adverse reactions occurred in both groups. Conclusion Oxytocin combined with misoprostol can effectively prevent postpartum hemorrhage, which deserves wide clinical promotion.