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5. Thrombospondin peptide ABT-898 inhibits inflammationand angiogenesis in a colitis model

Thrombospondin peptide ABT-898 inhibits inflammationand angiogenesis in a colitis model

来源 :世界胃肠病学杂志：英文版（电子版） | 被引量 : 0次 | 上传用户：yangrocpe

【摘 要】

：

AIM To evaluate the efficacy of the improvedthrombospondin mimetic peptide ABT-898 in a murinemodel of ulcerative colitis.METHODS： The dextran sodium sulfate （DSS

【作 者】

：

Linda S Gutierrez  Jun Ling  D 

【机 构】

：

LindaSGutierrez,JunLing

【出 处】

：

世界胃肠病学杂志：英文版（电子版）

【发表日期】

：

2015年20期

【关键词】

：

THROMBOSPONDIN 1 ABT-898 ABT-510 ANGIOGENESIS Inflammatory bowel disease Dextran 

【基金项目】

：

Supported by National Institutes of Health(AREA),No.R15 DK067901-02,the Howard Hughes Medical Institute,No.52006328,Wilkes Mentoring funds and institutional funds from Wilkes University and TCMC

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AIM To evaluate the efficacy of the improvedthrombospondin mimetic peptide ABT-898 in a murinemodel of ulcerative colitis.METHODS： The dextran sodium sulfate （DSS） wasused for the induction of colitis in both TSP-1 deficient（TSP-1-/-） and wild type （WT） m

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