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白血病是一种造血系统的恶性增殖性疾病,它严重地威胁着患者的生命。多年来,一直受到世界各国人们的关注。因此,白血病的研究国内外都倾注了极大的努力。20世纪60年代以来,白血病的研究在不少方面获得较大的进展,而染色体的研究亦取得可喜的成果。特别是1970年显带技术的问世,使白血病染色体的研究又大大地前进了一步。通过染色体的研究对白血病的病因、发病机制、诊断、治疗、预防和预后都提供了一定的科学依据。目前染色体在白血病的研究中应用日益广泛,因而受到人们的重视。现将白血病与染色体的新近资料作一简要地综述,重点介绍显带研究的文献。
Leukemia is a malignant and proliferative disease of hematopoietic system, which seriously threatens the life of the patient. Over the years, people in all countries in the world have been paying attention. Therefore, leukemia research both at home and abroad have devoted a great deal of effort. Since the 1960s, the research on leukemia has made great progress in many aspects, and the chromosomal research has also achieved gratifying results. In particular, the advent of banding technology in 1970 brought the research on leukemia chromosomes a step further. Chromosomes provide a scientific basis for the etiology, pathogenesis, diagnosis, treatment, prevention and prognosis of leukemia. At present, chromosomes are widely used in the research of leukemia, which has attracted people’s attention. A brief overview of recent data on leukemia and chromosomes is given, highlighting the literature on zonal studies.