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目的通过检测深圳居民血清中甲型H1N1流感抗体水平,了解相关的影响因素,为有效预防和控制甲型H1N1流感疫情提供有效科学依据。方法随机选取480位深圳居民作为观察对象,采用血凝抑制方法进行甲型H1N1流感抗体水平检测。并进行问卷调查,用SPSS16.0软件对血清抗体水平与不同流行病学指标之间进行相关因素分析。结果通过研究发现,年龄和甲流疫苗接种史与血清中甲型H1N1流感抗体水平显著性相关。6~15岁人群与已接种甲流疫苗人群血清中的甲型H1N1流感抗体阳性率显著性高于其它人群,阳性率分别是34.1%和48.1%。所有调查对象中,甲型H1N1流感疫苗接种率较低,仅为11.25%,6~15岁人群的疫苗接种率最高,为41.76%。结论青少年为甲型H1N1流感高危人群,加强对该人群的免疫接种,可对甲型H1N1流感的疫情控制起到显著成效。
Objective To detect the level of Influenza A (H1N1) antibody in serum of Shenzhen residents and understand the related factors so as to provide an effective scientific basis for the effective prevention and control of the outbreak of Influenza A (H1N1). Methods A total of 480 Shenzhen residents were randomly selected as observation subjects. The level of antibody against influenza A (H1N1) was detected by hemagglutination inhibition test. And questionnaire survey, using SPSS16.0 software on serum antibody levels and different epidemiological indicators between the relevant factors. Results The study found that age and history of influenza A H1N1 influenza vaccine serum antibody levels were significantly correlated. The positive rate of the influenza A (H1N1) antibody in the serum of 6-15-year-olds and those who had inoculated with the A-H1N1 vaccine was significantly higher than that of other populations, the positive rates were 34.1% and 48.1% respectively. Among all the respondents, the vaccination rate of Influenza A (H1N1) was 11.25%, while the vaccination rate was 41.76% among those aged 6-15 years. Conclusion Adolescents are at high risk for Influenza A (H1N1) and strengthening immunization against this group of people can have a significant effect on the control of the epidemic of Influenza A (H1N1).