氨苄青霉素广泛用于临床,其速发型过敏反应已被众所周知,而对其迟发型反应常常忽视。本文介绍3例因静点氨基苄青霉素引起药热反应,希望能引起重视。例1:女,18岁,因先天性脑性麻痹,于1988—03—15入院。于4月在硬膜外麻醉下行双下肢肌腱延长移植术。术后连续静点氨苄青霉素8g,加入10％葡萄糖液500m1中,1次/d,计3d,均于静点结束3h左右出现发热,体温在38～39℃,次日晨降到正常。 Ampicillin is widely used clinically, and its immediate-onset hypersensitivity reaction has been well known, and its late-onset response is often overlooked. This article describes three cases due to static point of ampicillin caused Pyrex reactions, hoping to attract attention. Example 1: Female, 18 years old, admitted to hospital on 1988-03-15 due to congenital cerebral palsy. In April in the epidural anesthesia under the lower limb tendon lengthening transplantation. Ampicillin 8g after continuous static point, add 10% glucose solution 500m1, 1 times / d, total 3d, were in the static point about 3h fever, body temperature at 38 ~ 39 ℃, the next morning down to normal.