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本组自１９８６年１０月～１９９２年９月在青海省２２所医院内进行６年出生缺陷动态监测、共监测围产儿６８９３２例，检出畸形儿６８４例，出生缺陷发生率９．９２‰，城市发生率１１．０１％，农村发生率９．４１‰，牧区发生率７．４８‰。自１９８６年开始动态监测、出生缺陷发生率逐年下降，由２２．６６‰下降至５．２９‰（１９９２年）。出生缺陷发生顺位：第一，领面部、畸形１９５例占２８，６％，其中唇裂、腭裂１１０例居多数；第二，中枢神经系统畸形１７６例占２５．８％；第三，肌肉骨骼系统畸形１６９例占２４．８％；第四，泌尿生殖系统畸形４２例占６．２％；第五，消化系统畸形３４例占４．９％，末组有６种畸形发生率最高，依次为①唇裂、腭裂；②多指（趾）；③脑积水；④马蹄内、外翻；⑤无脑儿；⑥开放性脊柱裂。本组围产儿死亡１５８例，死亡率２３０．９９‰。
The group from 1986 October to 1992 September in 22 hospitals in Qinghai Province, 6-year dynamic monitoring of birth defects, monitoring a total of 68,932 perinatal children, detected 684 cases of deformed children, the incidence of birth defects 9.92 ‰, The urban incidence rate was 11.01%, the rural incidence rate was 9.41%, and the pastoral area rate was 7.48%. Since the beginning of dynamic monitoring in 1986, the incidence of birth defects has been declining from 22.66 ‰ to 5.92 ‰ (1992). Birth defect occurred in the same order: First, the collar department, deformity 195 cases accounted for 28.6%, of which cleft lip and cleft palate 110 cases the majority; second, 176 cases of central nervous system malformations accounted for 25.8%; third, musculoskeletal 169 cases of systemic malformations accounted for 24.8%; Fourth, 42 cases of genitourinary system malformations accounted for 6.2%; Fifth, 34 cases of digestive system malformations accounted for 4.9%, the final group of 6 kinds of deformities highest incidence, followed by ① cleft lip, cleft palate; ② fingers (toe); ③ hydrocephalus; ④ horseshoe, valgus; ⑤ no brain children; ⑥ open spina bifida. 158 cases of perinatal death in this group, the mortality rate of 230.99 ‰.