论文部分内容阅读
目的:探讨血浆同型半胱氨酸水平与脑梗死动脉粥样硬化的关系。方法:动脉粥样硬化性脑梗死患者88例(脑梗死组),同期健康体检者40例(对照组),根据颈动脉多普勒彩色超声检查结果将脑梗死组分为脑梗死A组(有斑块)和脑梗死B组(无斑块),将对照组分为对照组A(有斑块)和对照B组(无斑块)。测定研究对象血浆同型半胱氨酸水平,并进行比较。结果:脑梗死组血浆同型半胱氨酸水平和颈动脉斑块数均高于对照组,差异均有统计学意义(P<0.05);有斑块组同型半胱氨酸水平高于无斑块组,差异有统计学意义(P<0.05)。结论:血浆同型半胱氨酸水平与动脉粥样硬化和脑梗死密切相关,可能是动脉粥样硬化的危险因素之一。
Objective: To investigate the relationship between plasma homocysteine level and atherosclerosis in cerebral infarction. Methods: 88 patients with cerebral infarction (cerebral infarction group) and 40 healthy subjects (control group) undergoing atherosclerotic cerebral infarction were divided into three groups according to color Doppler echocardiography: With plaque) and cerebral infarction group B (no plaque). The control group was divided into control group A (plaque) and control group B (no plaque). Plasma homocysteine levels were measured and compared. Results: The levels of plasma homocysteine and carotid plaques in cerebral infarction group were significantly higher than those in control group (P <0.05). The levels of homocysteine in plaque group were higher than those without plaque Block group, the difference was statistically significant (P <0.05). Conclusion: Plasma homocysteine level is closely related to atherosclerosis and cerebral infarction, which may be one of the risk factors of atherosclerosis.