碘伏的杀菌效力已被广大医务人员所认识,它的应用范围也逐步在扩大。由于使用碘伏有不产生抗药菌株的特点,已引起人们的注意,不少报道将其应用于烧伤病人创面防止继发感染取得了满意的临床效果。本文以人工烧伤的小白鼠为实验模型,用碘伏湿敷于烧伤创面,测定动物血清中谷丙转氨酶含量,并对动物肝脏进行病理组织学检查以了解其毒性反应。实验方法 BALb/c 小鼠随意分成7组,每组10只,除一组作正常值测定外,其它6组小鼠背部剪毛处用3cm 直径规格板压于脊椎侧面皮肤上,用烧伤的酒精棉球熨伤,使皮肤稍有隆起,触之有硬结,在烧伤处用刀划破约1cm 小口,烧伤面积约占小鼠皮肤总面 The efficacy of iodophor disinfection has been recognized by the majority of medical staff, and its scope of application is gradually expanding. Due to the use of iodophor does not produce drug-resistant strains of the characteristics that have attracted people’s attention, many reports will be applied to the burn wounds to prevent secondary infection has achieved satisfactory clinical results. In this paper, artificial burns mice as experimental model, with iodophor wet compress on burn wounds, measured in animal serum alanine aminotransferase levels, and animal liver histopathological examination to understand its toxicity. Experimental methods BALB / c mice were divided into 7 groups at random, 10 rats in each group. Except for one group, the other 6 mice were sheared on the back with 3 cm diameter plate on the lateral skin of the spine, Tissue cotton ironing, the skin slightly uplift, touching the induration, burned at the knife cut about 1cm small mouth, burns area accounts for about the total skin of mice