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为探讨急性高山反应的生理学评价方法,以12名男性青年为受试对象,每人参加三次低压舱实验(模拟海拔高度为5000m),进行症状学调查的同时,测量f、V_E、P_AO_2、PaO_2、AaDO_2、P_ACO_2、PaCO_2和pH_a。结果表明,急性高山反应重者,PaO_2较低,AaDO_2较高,反应轻者,PaO_2较高,A_aDO_2较低。在此基础上,到青藏高原(海拔4700m)对52名受试者进行症状学调查的同时,测量PaO_2和AaDO_2,其结果同上。可见,急性高山反应程度与PaO_2和AaDO_2大小有密切关系。因此,我们用PaO_2和AaDO_2作为评价指标,并建立了判别式和判别图。为验证该判别式和判别图的准确性和实用性,又到青藏高原(海拔4700m)观察174名男性青年,用症状学和判别式两种方法评价急性高山反应,两种方法判定结果的总吻合率达89.0％。
In order to explore the physiological evaluation method of acute alpine reaction, 12 male youths were enrolled in this study. Each of them participated in three experiments of low-pressure cabin (simulated elevation of 5000m), carried out the investigation of symptomology, and measured f, V_E, P_AO_2 and PaO_2 , AaDO_2, P_ACO_2, PaCO_2 and pH_a. The results showed that in the severe alpine reaction, PaO_2 was lower, AaDO_2 was higher, light reaction was observed, PaO_2 was higher and A_aDO_2 was lower. On this basis, 52 volunteers were surveyed on the Qinghai-Tibet Plateau (4700m above sea level) for symptomology, and PaO_2 and AaDO_2 were measured at the same time. It can be seen that the degree of acute alpine reaction is closely related to the size of PaO_2 and AaDO_2. Therefore, we use PaO_2 and AaDO_2 as evaluation indicators and establish discriminant and discriminant maps. In order to verify the accuracy and practicability of the discriminant and the discriminant map, 174 young men were also observed in the Qinghai-Tibet Plateau (4700m above sea level). The acute mountain reaction was evaluated by both symptomology and discriminant methods. The coincidence rate reached 89.0%.