A closed analytical relation is derived for the two-center nuclear attraction integrals over Slater type orbitals (STOs) in terms of binomial coefficients. This formula can be used in highly accurate calculations of the nuclear at-traction integrals. The relationships obtained are valid for arbitrary values of quantum numbers and screening con-stants of STOs and location of nuclei. A closed analytical relation is derived for the two-center nuclear attraction integrals over Slater type orbitals (STOs) in terms of binomial coefficients. This formula can be used in highly accurate calculations of the nuclear at-traction integrals. The relationships obtained are valid for arbitrary values ​​of quantum numbers and screening con-stants of STOs and location of nuclei.