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目的探讨心电图 QTc 延长与动脉粥样硬化的关系,开发动脉粥样硬化的诊断指标。方法用高分辨率彩色超声诊断仪扫查22例 QTc 延长患者与30例 QTc 正常对照者的颈动脉,比较两组间颈总动脉内-中膜厚度、粥样硬化斑块阳性率及颈总动脉血流动力学指标的差异。结果 QTc 延长组颈总动脉内-中膜厚度较正常对照组增厚,动脉粥样硬化斑块阳性率增加,颈总动脉血流动力学指标无明显差异。结论 QTc 延长与颈总动脉的内-中膜厚度、颈动脉粥样硬化斑块阳性率有明显的相关性,提示 QTc 延长可作为亚临床动脉粥样硬化的指标之一。
Objective To explore the relationship between QTc prolongation and atherosclerosis and to develop a diagnostic index for atherosclerosis. Methods Twenty-two carotid arteries of QTc prolonged patients and 30 QTc normal controls were scanned by high-resolution color sonography. The intima-media thickness, the positive rate of atherosclerotic plaque and the total carotid artery Differences of arterial hemodynamic indexes. Results The thickness of intima-media thickness of common carotid artery in QTc prolonged group was thicker than that in normal control group, the positive rate of atherosclerotic plaque was increased, and there was no significant difference in common carotid artery hemodynamics. Conclusions The prolongation of QTc has obvious correlation with the carotid artery intima - media thickness and carotid atherosclerotic plaque positive rate, suggesting that QTc prolongation can be used as one of the indicators of subclinical atherosclerosis.