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粉防已甲素和乙素对L7712和S180癌细胞DNA合成的ID_(50)分别为2.6,3.5和27.5,24.5mg/L;它们对L7712细胞DNA合成的抑制是由DNA复制模板受到损伤而引起的。它们对两种癌细胞DNA和RNA的合成有很强的抑制作用,对蛋白质合成的抑制作用较弱。两种药物对癌细胞抑制程度和作用方式相似。
The ID_(50) of the DNA synthesis of anticancer A and B on L7712 and S180 cancer cells was 2.6, 3.5, 27.5, and 24.5 mg/L, respectively; their inhibition of DNA synthesis in L7712 cells was damaged by DNA replication templates. caused. They have a strong inhibitory effect on the synthesis of both cancer cells DNA and RNA, and have a weak inhibitory effect on protein synthesis. The degree of inhibition and the mode of action of the two drugs on cancer cells are similar.