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目的 观察生长抑素联合奥美拉唑控制难治性非食道静脉曲张性消化道大出血的疗效。方法 3 0例难治性消化道出血病人给予生长抑素 (somatostatin ,施他宁 )剂量首次 2 5 0 μg静注 ,之后再以 60 0 0μg/ 2 4h静滴 ,同时加用奥美拉唑 40mg静脉注射 ,每 4h一次 ,两药共同使用 3～ 5d。 结果 显效 2 0例(66 6% ) ,平均用药后止血时间 18± 6h ;有效 6例 (2 0 % ) ,平均用药后止血时间为 48± 2 4h ,总有效率为86 6%。结论 生长抑素联合奥美拉唑控制难治性非静脉曲张性消化道大出血 ,止血率高 ,副作用小 ,有推广价值
Objective To observe the effect of somatostatin combined with omeprazole in refractory non-esophageal variceal hemorrhage. Methods Thirty patients with refractory gastrointestinal bleeding were given intravenous infusion of somatostatin (somatostatin) for the first time, and intravenous infusion of 60 0 0μg / 2 4h followed by omeprazole 40mg intravenously, once every 4h, two drugs commonly used 3 ~ 5d. The results showed that 20 cases (66.6%) were markedly effective. The mean time to hemostasis was 18 ± 6 hours after treatment. The effective rate was 6 cases (20%). The mean time to hemostasis was 48 ± 24 hours. The total effective rate was 86.6%. Conclusion Somatostatin combined with omeprazole in the control of refractory non-variceal hemorrhage, hemostasis rate, side effects, there is a promotional value