湖南省钩端螺旋体病地理流行病学研究

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一、本文用地理流行病学、描述流行病学,血清流行病学等多种方法对湖南省36年钩体病进行了综合分析,阐明了我省钩体病疫区分布、流行强度、流行形式,查明了主要宿主及菌群(型)分布,人群带菌菌群以及血清抗体水平,对今后防治工作有意义。二、发病率以Ⅳ区湘东丘陵区16.78/10万最高,其次是Ⅵ区洞庭平原区次之14.86/10万,Ⅴ区湘中丘陵区4.62/10万最低。三、我省钩体病自1958~1993年以来,平均发病率为9.01/10万,平均病死率为3.11%,1973、1987、1993年曾出现过三次大流行,发病率分别为46.8/10万、22.48/10万、20.68/10万。流行主要形式是稻田型。四、病人菌群13群,血清抗体为14群。按地理区划病人菌群分布以Ⅴ区、Ⅳ区最复杂,有12群;Ⅰ区为3群,较简单;血清抗体Ⅳ区为14群,Ⅰ区为6群。病人分离菌群与血清抗体群在相同的地理区划显示相符。五、7种家畜、家禽所带菌群可分为9群。猪带菌9群,最复杂;犬带菌3群、驴带2群、牛的标本仅分出一株未定群。从血清抗体来看,猪血清抗体最为复杂;牛次之、犬感染9群。猪主要为圈养,活动范围局限,在我省不是主要传染源;犬带犬群,曾引起个别地? In this paper, a comprehensive analysis of 36-year-old leptospirosis in Hunan Province was carried out with various methods such as geographic epidemiology, epidemiology and serological epidemiology, and the distribution, prevalence and prevalence of leptospirosis in Hunan Province were clarified. , Identified the main host and flora (type) distribution, population of bacteria and serum antibody levels, the future work of prevention and treatment is meaningful. Second, the incidence of hilly areas in the eastern part of the Ⅳ district 16.78 / 100000 highest, followed by Ⅵ Dongting plain area 14.86 / 100000, Ⅴ area hilly area 4.62 / 100000 lowest. Third, our province leptospirosis since 1958 ~ 1993, the average incidence rate of 9.01 / 100,000, the average mortality rate was 3.11%, 1973, 1987, 1993, there have been three pandemic, the incidence rates were 46.8 / 100,000, 22.48 / 100,000, 20.68 / 100,000. The main form of pop rice field type. Fourth, the patient flora 13 groups, serum antibody 14 group. According to the geographic division of the distribution of patients with Ⅴ district, Ⅳ district is the most complex, 12; Ⅰ area is 3 groups, relatively simple; Ⅳ antibody antibody group 14, Ⅰ area 6 groups. Patient isolation and antibody serogroups showed the same geographical divisions. Five, seven kinds of livestock, poultry carrying bacteria can be divided into nine groups. Swine with bacteria 9 groups, the most complex; dogs with bacteria 3 groups, donkey with 2 groups, cattle specimens were divided into only one undetermined group. Antibodies from the serum point of view, the most complex antibody to pig serum; second, dogs infected 9 groups. Pig is mainly captive, the scope of activities is limited, in our province is not the main source of infection; dogs with dogs, had caused by individual?
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