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目的:探讨血清细胞间粘附分子- 1 ( ICAM- 1 )、血管粘附蛋白- 1 ( VAP- 1 )、抗氧化低密度脂蛋白抗体( o L AB)和C-反应蛋白( CRP)水平变化与不同类型心脑血管疾病间的关系。方法:以EL ISA法检测了62例心脑血管病患者和2 3例健康体检者血清ICAM- 1、VAP- 1、o LAB和CRP。结果:急性心肌梗死和冠心病患者血清ICAM- 1、VAP- 1、o LAB和CRP均高于对照组;而脑梗死患者的ICAM- 1与对照组无显著性差异。结论:血清ICAM- 1、VAP- 1、o LAB和CRP水平变化与不同类型的心脑血管疾病有关。
Objective: To investigate the changes of serum levels of ICAM-1, VAP-1, o L AB and CRP Relationship between changes and different types of cardiovascular and cerebrovascular diseases. Methods: Serum ICAM-1, VAP-1, o LAB and CRP were detected by ELISA in 62 patients with cardio-cerebrovascular disease and 23 healthy subjects. Results: The serum levels of ICAM-1, VAP-1, o LAB and CRP in patients with acute myocardial infarction and coronary heart disease were significantly higher than those in the control group. ICAM-1 in patients with cerebral infarction was not significantly different from that in the control group. Conclusion: The changes of serum ICAM-1, VAP-1, o LAB and CRP levels are related to different types of cardiovascular and cerebrovascular diseases.