Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyc

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：ZPHZPH

【摘要】

：

Increasing the self-resistance levels of Streptomyces is an effective strategy to improve the production of antibiotics.To increase the oxytetracycline(OTC) pro

【作者】

：

Shouliang Yin Xuefeng Wang Min

【机构】

：

StateKeyLaboratoryofMicrobialResources,DepartmentofEnvironmentalandBiologicalEngineering,ShengxueDac

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2017年9期

【关键词】

：

抗生素生产龟裂链霉菌抗性基因土霉素 STREPTOMYCES 过度表达重组菌株合作 resistance genes oxytetracycline

【基金项目】

：

supported by funding from Shengxue Dacheng Pharmaceutical Co.,Ltd,National Natural Science Foundation of China（31400034 and 31570031）, the Ministry of Science and Technology of China（2013CB734001）

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Increasing the self-resistance levels of Streptomyces is an effective strategy to improve the production of antibiotics.To increase the oxytetracycline(OTC) production in Streptomyces rimosus,we investigated the cooperative effect of three co-overexpressi

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Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyc

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