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吩哌啶(Phenoperidine)是一高效麻醉性镇痛药,由哌替啶(meperidine,pethid-ine)的甲基以苯异丙醇代替而成。该药具有作用快、药效时间短、不良反应轻等优点;但有成瘾的缺点。临床上国外已有近20年的应用历史。现将我院在试制中的路线、药理和临床应用的情况,总结简介如下。
Phenoperidine is a highly potent narcotic analgesic, which is made from the methyl group of meperidine (pethid-ine) substituted with benzene isopropanol. The drug has the effect of fast, short effective time, adverse reactions and other advantages; but there are disadvantages of addiction. Clinically, nearly 20 years of applied history abroad. Now my hospital trial in the line, pharmacology and clinical application of the situation, summarized as follows.