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目的：观察果糖二磷酸钠（ＦＤＰ）治疗急性脑梗死的疗效及不良反应。方法：将８０例经ＣＴ或ＭＲＩ证实的急性脑梗死病人随机分为２组。ＦＤＰ组４０例（男性２６例，女性１４例；年龄６４±ｓ１７ａ）用ＦＤＰ２０ｇ，静脉滴注ｑｄ×２０ｄ。对照组４０例（男性２８例，女性１２例；年龄６７±１７ａ）用右旋糖酐－４０葡萄糖注射液５００ｍＬ加复方丹参注射液２０ｍＬ，静脉滴注ｑｄ×２１ｄ。结果：ＦＤＰ组总有效率为７８％，对照组总有效率为５３％，Ｐ＜０．０５。治疗期间未发现任何不良反应。结论：ＦＤＰ治疗急性脑梗死是安全、有效的。
Objective: To observe the efficacy and adverse reactions of fructose diphosphate (FDP) in the treatment of acute cerebral infarction. Methods: Eighty patients with acute cerebral infarction confirmed by CT or MRI were randomly divided into two groups. FDP group of 40 patients (26 males and 14 females; age 64 ± s17a) with FDP20g, intravenous drip qd × 20d. The control group of 40 patients (28 males and 12 females; age 67 ± 17a) with dextran-40 glucose injection 500mL Fufang Danshen injection 20mL, intravenous drip qd × 21d. Results: The total effective rate was 78% in FDP group and 53% in control group, P <0.05. During the treatment did not find any adverse reactions. Conclusion: FDP is safe and effective in treating acute cerebral infarction.