过去十几年的研究表明,双酚A与17β-雌二醇相比具有轻度的雌激素活性。在动物模型中,双酚A已被证实具有多种不利影响,主要涉及生殖内分泌学。早期研究表明,青春期前暴露于双酚A可以加速母鼠青春期的发动,但降低了生殖数量。双酚A对性早熟的影响仍有争议,动物实验的研究结果外推到人类,由于物种代谢的特异性,因此此结果需要进一步审 Studies over the past dozen years have shown that bisphenol A has mild estrogenic activity compared to 17β-estradiol. Bisphenol A has been shown to have several adverse effects in animal models, mainly involving reproductive endocrinology. Early studies showed that preadolescent exposure to bisphenol A can accelerate mothers’ onset of puberty, but reduce reproductive numbers. The impact of bisphenol A on precocious puberty remains controversial and the results of animal experiments are extrapolated to humans and due to the specificity of species metabolism this result requires further examination