最近二十年来,缺血性心脏病心肌病理学上一个主要进展,是认识到心肌在不同程度缺血情况下,能发生“顿抑(stunned)”,“冬眠(hibernating)”甚至“僵直(Embalmed)”。在冠脉血流恢复后,这些心肌能部分的或完全的重新恢复它的功能。这一发现给研究和治疗产生了深远的影响。引起研究者和临床医生广泛的关注。当前,依据它们存在的条件和反应特征,将缺血性心肌作如下分类(见表Ⅰ)。本文将重点综述顿抑和冬眠心肌的定义、特征、机制和临床重要意义。 A major advance in cardiomyopathology of ischemic heart disease over the last two decades has been the recognition that “myocardial stunned,” “hibernating,” or even “stiff” Embalmed ". After the coronary blood flow is restored, these myocardium can partially or completely regain its function. This finding has had a profound impact on research and treatment. Aroused widespread concern of researchers and clinicians. Currently, ischemic myocardium is classified as follows (see Table I) based on their presence and response characteristics. This article will focus on the definition of stunned and hibernating myocardium, features, mechanisms and clinical significance.