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目的分析孕前和孕期妇女细小病毒B 19(human parvovirus B 19,简称B 19)感染情况,为临床医生提供参考。方法采用酶联免疫的方法对2013~2015年来广西壮族自治区妇产医院就诊的18~45岁孕前及孕期妇女血清中细小病毒B 19的特异性抗体IgM进行检测,并按照不同条件进行分析。结果 B19 IgM抗体阳性率2013年11.34%,2014年4.93%,2015年8.75%;不同年龄段的阳性率差异无统计学意义(P>0.05);第三、第四季度感染率高于其它季度,不同季节之间差异有统计学意义(P<0.05)。结论南宁地区育龄妇女B 19感染率较高,应广泛检测,提高优生优育质量。
Objective To analyze the infection status of human parvovirus B 19 (B 19) in pre-pregnancy and post-pregnancy women, and provide a reference for clinicians. Methods Serum IgM of parvovirus B 19 was detected by enzyme-linked immunosorbent assay (ELISA) in the serum of pregnant women aged 18-45 years from 2013 to 2015 in Maternity Hospital of Guangxi Zhuang Autonomous Region and analyzed according to different conditions. Results The positive rate of B19 IgM antibody was 11.34% in 2013, 4.93% in 2014 and 8.75% in 2015. There was no significant difference in the positive rates of different age groups (P> 0.05). The infection rates in the third and fourth quarters were higher than those in other quarters , The difference between different seasons was statistically significant (P <0.05). Conclusion The prevalence of B 19 in women of childbearing age in Nanning is relatively high and should be widely tested to improve the quality of prenatal and postnatal care.