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嗜酸细胞增多肌痛综合征(EMS)的特征为摄入左旋色氨酸的病人外周血嗜酸细胞增多和肌痛,与嗜酸性筋膜炎(EF)在临床上、组织学上有着许多相同的特征。近来有人提出摄入左旋色氨酸与EF有联系,尤其是1988年10月～1989年6月间某公司生产的被污染的左旋色氨酸与EMS相关。为此作者将左旋色氨酸相关的EF和特发性EF的临床与实验室特征作了比较。 51例皮肤纤维变性的病例中19例EF、10例局限性硬皮病和22例系统性硬化症。17例(因故剔除2例)EF病人中11例(65%)为女性,发病前摄入过左旋色氨酸,每日量
Eosinophilic myalgia syndrome (EMS) is characterized by peripheral blood eosinophilia and myalgia in patients taking L-tryptophan, clinically and histologically many with eosinophilic fasciitis (EF) The same characteristics. Recently, it has been suggested that the intake of L-tryptophan and EF have been linked, especially from October 1988 to June 1989, a company produced contaminated L-tryptophan and EMS related. For this reason, the authors compared the clinical and laboratory characteristics of L-tryptophan-associated EF with idiopathic EF. Of the 51 cases of skin fibrosis, 19 were EF, 10 were localized scleroderma, and 22 were systemic sclerosis. Eleven patients (65%) of 17 patients (2 were excluded for some reason) of EF were female, with pretreatment L-tryptophan intake, daily dose