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目的探讨术前、术后应用消炎痛联合小梁切除术治疗新生血管性青光眼的疗效。方法对43例43眼新生血管性青光眼患者,术前、术后口服消炎痛并行小梁切除术,术后随访6~12个月,观察患者术后眼压、视力、前房角、虹膜的变化情况。结果随访结束,术眼眼压降至21mmHg以下者29眼(67.44%),24~42mmHg者11眼(25.58%),42mmHg以上3眼(6.98%)。36眼视力维持在术前水平(83.72%),7眼视力下降(16.28%)。Schelemm氏管充血消失及新生血管部分闭塞21眼(48.84%),前房角无变化17眼(39.54%),前房角粘连范围增加5眼(11.63%)。虹膜粗大血管变细或消除23眼(53.49%),无明显变化15眼(34.88%),虹膜新生血管变粗大5眼(11.63%)。结论术前、术后服用消炎痛联合小梁切除术治疗新生血管性青光眼能取得较好的效果。
Objective To investigate the effect of indomethacin combined with trabeculectomy in the treatment of neovascular glaucoma before and after operation. Methods Forty - three 43 eyes of 43 patients with neovascular glaucoma underwent trabeculectomy combined with preoperative and postoperative oral administration of indomethacin. The patients were followed up for 6 to 12 months. The intraocular pressure, visual acuity, anterior chamber angle, iris Changes. Results At the end of follow-up, 29 eyes (67.44%) with intraocular pressure drop below 21mmHg, 11 eyes (25.58%) with 24 ~ 42mmHg, and 3 eyes (6.98%) with 42mmHg or above. 36 eyes maintained at the preoperative level (83.72%), 7 eyes decreased vision (16.28%). There were 21 eyes (48.84%) with Schelemm’s disappearance of hyperemia and partial neovascular occlusion, 17 eyes (39.54%) with no changes in anterior chamber angle and 5 eyes (11.63%) with anterior chamber angle attachment. There were 23 eyes (53.49%), 15 eyes (34.88%) with no obvious change, and 5 eyes (11.63%) with thick iris neovascularization. Conclusion Preoperative and postoperative administration of indomethacin combined with trabeculectomy for neovascular glaucoma can achieve better results.