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本文比较分析了18例神经母细胞瘤的DNA含量、N-myc基因扩增、临床分期、原发部位等因素与预后的关系。结果表明,有N-myc基因扩增的死亡率(7/10)明显高于无扩增的(1/8);DNA、含量增高与肿瘤的恶性度成正比;临床分期与N-myc基因扩增情况相结合与病死率的关系极为密切。
This article comparative analysis of 18 cases of neuroblastoma DNA content, N-myc gene amplification, clinical stage, the primary site and other factors and prognosis. The results showed that the mortality rate of N-myc gene amplification (7/10) was significantly higher than that of non-amplification (1/8). The DNA content was positively correlated with the malignancy of the tumor. The clinical stage was related to the N-myc gene The combination of amplification and mortality is extremely close.