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皮质醇(F)是人体的一种生理作用最为广泛的肾上腺皮质激素,它不仅对调节人体的三大营养物质:糖、脂肪和蛋白质的代谢发挥重要作用,对抗炎、抗毒、抗过敏发挥重要作用,而且对免疫系统和其他内分泌系统亦发挥非常重要的作用。在当前临床医学和药物学的研究中,测定受试者F的水平是一项重要的指标。在哺乳动物中,树鼩是仅次于猕猴的较接近人类的动物,在某种治疗方法和药物研究的基础阶段,选择树鼩为实验动物为较佳方案。人的F分泌具有明显的昼夜节律,欲用树鼩代替人作有关F的研究,就必须首先研究树鼩F分泌的昼夜节律,基于此目的,我们开展了该项研究。
Cortisol (F) is the most widely used adrenal cortical hormone in the body. It not only plays an important role in regulating the metabolism of the three major nutrients of human body, such as sugar, fat and protein, but also has anti-inflammatory, antitoxic and antiallergic effects Play an important role, but also the immune system and other endocrine system also play a very important role. In current clinical and pharmacological studies, determining the level of F in a subject is an important indicator. In mammals, tree shrews are second only to rhesus macaques than human beings. In the basic stage of some treatment and drug research, selecting tree shrews as experimental animals is the best option. Human F secretion has a significant circadian rhythm. If we want to use tree shrew instead of humans to study F, we must first study the circadian rhythm of tree shrew F secretion. For this purpose, we conducted this study.