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目的研究益气通里中药对直肠癌患者术后胃肠及免疫功能影响。方法 44例直肠癌术后患者,采取数字随机法分成观察组和对照组,各22例。对照组采取常规治疗,观察组在对照组基础上采取益气通里中药治疗。比较两组术后胃肠功能及免疫功能。结果观察组患者排便恢复正常时间、排气恢复正常时间均短于对照组,差异均有统计学意义(P<0.05)。观察组患者术后免疫球蛋白(Ig)A、IgG、IgM水平均高于术前,差异均有统计学意义(t=5.600、3.448、3.643,P<0.05)。对照患者术后IgA、IgG、IgM水平与术前比较,差异均无统计学意义(t=0.690、0.482、0.651,P>0.05)。观察组患者术后IgA、IgG、IgM水平均高于对照组,差异均有统计学意义(P<0.05)。两组患者治疗期间,未发生严重不良反应。结论益气通里中药对直肠癌患者术后胃肠及免疫功能具有有利影响,临床价值较高。
Objective To study the effects of Yiqi Tongli on gastrointestinal and immune function in patients with rectal cancer after operation. Methods Forty-four patients with postoperative rectal cancer were divided into observation group and control group by digital random method, with 22 cases in each group. Control group to take conventional treatment, observation group on the basis of the control group to take Yiqi Tongli Chinese medicine treatment. The postoperative gastrointestinal function and immune function were compared between the two groups. Results The defecation recovery time and exhaust recovery time in the observation group were shorter than those in the control group (P <0.05). The levels of immunoglobulin (Ig) A, IgG and IgM in observation group were significantly higher than those before surgery (t = 5.600, 3.448, 3.643, P <0.05). There was no significant difference in the levels of IgA, IgG and IgM between the two groups after operation (t = 0.690,0.482,0.651, P> 0.05). The levels of IgA, IgG and IgM in the observation group were significantly higher than those in the control group (P <0.05). Two groups of patients during treatment, no serious adverse reactions. Conclusion Yiqi Tongli has a beneficial effect on the postoperative gastrointestinal and immune function of patients with rectal cancer, the clinical value is higher.