通过对新生期大鼠皮下注射谷氨酸单钠(MSG),观察对下丘脑內侧基底部神经元的影响?峁砻?MSG可毁损下丘脑弓状核、腹内侧核、具有明显的神经毒性作用,其毒性作用可能随着作用剂量的加大或时间的延长而增大。未见到MSG对下丘脑背内侧核神经元的损伤作用。 Through the subcutaneous injection of neonatal glutamate monosodium glutamate (MSG) to observe the medial hypothalamic basal ganglia neurons? 峁  砻? MSG can damage the hypothalamic arcuate nucleus, ventral medial nucleus, with significant Neurotoxicity, its toxic effects may increase with the role of dose or time increases. No effect of MSG on the dorsal medulla neurons in the hypothalamus was observed.