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目的:观察魔芋葡甘露聚糖(KGM)对代谢综合征患者的体重指数、腰围、血脂、血压、血糖等的影响。方法:86例代谢综合征患者在不改变原有治疗的基础上给予KGM口服,治疗12周后评价对体重指数、腰围、血脂、血压、血糖等的影响。结果:KGM降低体重指数、腰围、血压、总胆固醇、甘油三酯、低密度脂蛋白、空腹血糖、餐后2 h血糖、糖基化血红蛋白(P<0.01);升高高密度脂蛋白(P<0.01)。结论:KGM防治代谢综合征开发前景广阔。
Objective: To observe the effects of konjac glucomannan (KGM) on body mass index, waist circumference, blood lipids, blood pressure, blood sugar and so on in patients with metabolic syndrome. Methods: Eighty - six patients with metabolic syndrome were given oral KGM without changing the original treatment. After 12 weeks of treatment, the body mass index, waist circumference, blood lipids, blood pressure, blood glucose and other factors were evaluated. Results: KGM decreased body mass index, waist circumference, blood pressure, total cholesterol, triglyceride, low density lipoprotein, fasting blood glucose, postprandial 2h blood glucose and glycosylated hemoglobin (P <0.01) <0.01). Conclusion: KGM has a promising prospect in the prevention and treatment of metabolic syndrome.