原发性肝癌发生和转移是一个多环节、多因素的复杂过程。在肿瘤发生、启动、增生、癌变到转移的过程中,除基因水平的变化外,在分子水平还有不同的功能性蛋白的参与。蛋白质组学研究直接定位于蛋白质水平,从整体、动态、定量的角度去研究基因的功能。它不仅有助于进一步揭示肝癌 The occurrence and metastasis of primary liver cancer is a multi-link, multi-factor complex process. In the process of tumorigenesis, initiation, hyperplasia and carcinogenesis to metastasis, in addition to the change of gene level, there are different functional proteins involved in the molecular level. Proteomics research is located directly at the protein level, from a holistic, dynamic, quantitative point of view to study the function of genes. It not only helps to further reveal liver cancer