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目的通过注射康宁克通Ａ，观察增生性瘢痕内郎格罕细胞和肥大细胞数量和组织形态的变化。方法本组共９例增生性瘢痕，在注射康宁克通Ａ８ｄ后，取材，将同一病例分３处取材，即皮肤、瘢痕、用药处，进行计量和组织形态观察。结果（１）增生性瘢痕内郎格罕细胞和肥大细胞的数量较正常皮肤增高。（２）康宁克通Ａ可使增生性瘢痕内郎格罕细胞的数量减少、组织形态改变，但对肥大细胞无明显影响。结论通过对郎格罕细胞和肥大细胞的观察，对了解增生性瘢痕发生机制具有重要意义。
Objective To observe the changes of the number and morphology of Langerhans cells and mast cells in hypertrophic scar by injection of Kangningketong A. Methods A total of 9 cases of hypertrophic scars in this group, after injection of Corning Kay pass A8d, drawn, the same case divided into three parts, namely, skin, scar, medication, measurement and histological observation. Results (1) The number of Langerhans cells and mast cells in hypertrophic scars increased compared with normal skin. (2) Kangningketong A can reduce the number of Langerhans cells in hypertrophic scar, and change the tissue morphology, but have no obvious effect on mast cells. Conclusion The observation of Langerhans cells and mast cells is of great significance for understanding the mechanism of hypertrophic scar formation.