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[目的 ]研究刺莓果多糖对小鼠体液免疫调节功能的影响 .[方法 ]采用溶血空斑试验、白细胞介素 2活性测定、T细胞亚群测定等方法 .[结果 ]刺莓果多糖能使小鼠脾细胞对绵羊红细胞的免疫球蛋白M空斑形成细胞数明显增加 ,促进刀豆蛋白A刺激的小鼠脾细胞分泌白细胞介素 2 ,增高辅助性T细胞百分比及辅助性T细胞与抑制性T细胞比值 .[结论 ]刺莓果多糖能促进小鼠脾细胞产生特异性抗体 ,并通过影响辅助性T细胞分泌白细胞介素 2、辅助性T细胞与抑制性T细胞比值而参与免疫调节
[Objective] To study the effects of polysaccharides of T. chinensis on the humoral immunity of mice. [Methods] Hemolysis plaque assay, interleukin-2 activity assay, T-cell subpopulation assay, etc. [Results] Thornberry polysaccharides Increase the number of immunoglobulin M plaque-forming cells in mouse red blood cells by mouse spleen cells, promote the secretion of interleukin 2 by the mouse spleen cells stimulated by ConA, and increase the percentage of helper T cells and helper T cells. Inhibitory T cell ratio. [Conclusion] Spica polysaccharide can promote specific antibody production in mouse splenocytes and participate in immunization by affecting the ratio of helper T cells secreting interleukin-2, helper T cells and suppressor T cells. adjust