论文部分内容阅读
目的探讨MSCT增强扫描CT定量分析在骨巨细胞瘤的定性诊断中的应用价值。方法分别单独应用MSCT增强后强化CT值及强化CT值+年龄、部位和形态学特征等综合因素对我院329例溶骨性骨肿瘤或肿瘤样病变进行骨巨细胞瘤的前瞻性预判,分别划分骨巨细胞瘤组(实验组)与非骨巨细胞瘤组(对照组)进行统计学分析,定量研究CT增强扫描后CT值的变化特征,并追踪病理结果对照,最终有病理结果的186例中骨巨细胞瘤55例。结果在186例肿瘤或肿瘤样病变中,骨巨细胞瘤55例,增强后强化最显著区域平均CT值为(108±39)HU;非骨巨细胞瘤131例,增强后强化最显著区域平均CT值为(82±78)HU;二者差异有统计学意义(P<0.05)。当选取CT值临界点为97 HU为标准进行预判时,诊断骨巨细胞瘤的敏感性为87.27%,特异性为78.62%,诊断正确率为81.18%;同时结合患者年龄及发病部位、形态特征等综合因素进行预判时,诊断骨巨细胞瘤诊断的敏感性为96.36%,特异性为96.18%,诊断准确率为96.23%。结论CT增强扫描中CT值的定量分析在骨巨细胞瘤的定性诊断中有较好的导向价值,如果结合患者年龄及发病部位、形态学特征等综合因素进行预判,可以提高术前诊断正确率。
Objective To investigate the value of MSCT enhanced CT quantitative analysis in the diagnosis of giant cell tumor of bone. Methods A total of 329 cases of osteolytic bone tumor or tumor-like lesions in our hospital were prospectively evaluated by combined application of MSCT enhanced CT value, enhanced CT value, age, location and morphology. We divided the giant cell tumor of bone (experimental group) and the non-giant cell tumor group (control group) into statistical analysis, and quantitatively studied the change characteristics of CT value after CT enhanced scanning, and tracked the pathological results and finally the pathological results 186 cases of giant cell tumor in 55 cases. Results Of the 186 tumor or tumor-like lesions, 55 cases were giant cell tumor of bone. The average CT value of the most significant area of enhancement was (108 ± 39) HU. There were 131 cases of non-giant cell tumor, the most significant area of enhancement CT value was (82 ± 78) HU; the difference was statistically significant (P <0.05). When the critical value of CT was 97 HU, the sensitivity, specificity and accuracy of diagnosis of giant cell tumor of bone were 87.27%, 78.62% and 81.18% respectively. Combined with the age, Characteristics and other factors for the prediction of prognosis, the diagnosis of giant cell tumor of bone sensitivity was 96.36%, the specificity was 96.18%, the diagnostic accuracy was 96.23%. Conclusion The quantitative analysis of CT value in CT enhanced scan has a good guiding value in the qualitative diagnosis of giant cell tumor of bone. If combined with the factors such as age, disease location and morphological characteristics of patients, the preoperative diagnosis can improve the accuracy of preoperative diagnosis rate.