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目的探讨泮托拉唑联合醒脑静在预防中枢性应激性溃疡中的作用。方法将205例重型脑外伤、大面积脑梗死、脑出血病例,随机分为泮托拉唑治疗组(对照组),80例;泮托拉唑联合醒脑静治疗组(治疗组),125例,各自治疗1周。对比两组患者中枢性应激性溃疡发生率及病死率。结果治疗组中枢性应激性溃疡的发生率和死亡率明显低于对照组,差异具有显著性(P<0.05)。结论泮托拉唑联合醒脑静在预防中枢性应激性溃疡中的作用优于单独使用泮托拉唑者。
Objective To investigate the role of pantoprazole and xingnaojing in preventing central stress ulcer. Methods A total of 205 cases of severe traumatic brain injury, large area cerebral infarction and cerebral hemorrhage were randomly divided into pantoprazole group (control group) and 80 cases. Pantoprazole combined with xingnaojing group (treatment group), 125 For example, each treatment for 1 week. The incidence and mortality of central stress ulcer in both groups were compared. Results The incidence and mortality of central stress ulcer in the treatment group were significantly lower than those in the control group (P <0.05). Conclusions Pantoprazole combined with xingnaojing is better than pantoprazole alone in preventing central stress ulcer.